Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311964 | 0.82 | MAPT (0.57) | ADRB2HTR1AMAPTADRB1HTR2B | |
| Fumaric Acid SCHEMBL7312424 | 0.80 | ADRB2 (0.51) | ADRB2HTR1AMAPTADRB1HTR2B | |
| SCHEMBL10666924 | 0.75 | HTR1A (0.51) | ADRB2HTR1AMAPTADRB1HTR2B | |
| SCHEMBL7313353 | 0.72 | MAPT (0.55) | ADRB2HTR1AMAPTADRB1HTR2B | |
| SCHEMBL7302638 | 0.72 | ALDH1A1 (0.60) | ADRB2HTR1AADRB1HTR2BCYP2D6 | |
| SCHEMBL11197660 | 0.71 | MAPT (0.64) | ADRB2HTR1AMAPTADRB1HTR2B | |
| SCHEMBL7319524 | 0.71 | CASR (0.60) | ADRB2ADRB1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL10720250 | 0.71 | CYP2D6 (0.39) | ADRB2ADRB1CYP2D6HTR2AMEN1 | |
| SCHEMBL10721624 | 0.71 | CYP2D6 (0.39) | ADRB2ADRB1CYP2D6HTR2AMEN1 | |
| SCHEMBL7308129 | 0.70 | MAPT (0.53) | ADRB2HTR1AMAPTADRB1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |