Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443664 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1ALDH1A1 | |
| SCHEMBL8858130 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2BF10SIGMAR1PLA2G2A | |
| SCHEMBL7310384 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7314483 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BF10SIGMAR1 | |
| SCHEMBL7307345 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BF10SIGMAR1 | |
| SCHEMBL7316531 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7313985 | 0.81 | ITGB3 (0.60) | ITGB3ITGA2BF10SIGMAR1 | |
| SCHEMBL27442654 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BSIGMAR1ALDH1A1 | |
| SCHEMBL8858128 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BF10SIGMAR1PLA2G2A | |
| SCHEMBL7304501 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |