Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314436 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BF10SIGMAR1PLA2G2A | |
| SCHEMBL8858128 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BF10SIGMAR1PLA2G2A | |
| SCHEMBL7307345 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BF10SIGMAR1 | |
| SCHEMBL27363129 | 0.76 | PLA2G2A (0.37) | ITGB3ITGA2BF10PLA2G2AALDH1A1 | |
| SCHEMBL6606264 | 0.73 | ITGB3 (0.58) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL7307351 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2BF10SIGMAR1PLA2G2A | |
| SCHEMBL7230274 | 0.70 | ITGB3 (0.54) | ITGB3ITGA2BF10PLA2G2AALDH1A1 | |
| SCHEMBL7316619 | 0.69 | ITGB3 (0.51) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL27443664 | 0.67 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1ALDH1A1 | |
| SCHEMBL8892671 | 0.67 | ITGB3 (0.49) | ITGB3ITGA2BF10PLA2G2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |