SCHEMBL7314524

SCHEMBL7314524

O=C(O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.73
CTSB P07858 3/20 0.73
CTSS P25774 2/20 0.73
CTSK P43235 1/20 0.73
TACR1 P25103 2/20 0.67
MME P08473 1/20 0.63
ECE1 P42892 1/20 0.63
ALDH1A1 P00352 1/20 0.57
ALOX15 P16050 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9557048 1.00 CTSL (0.73) CTSLCTSBCTSSCTSKTACR1
SCHEMBL31207208 0.97 CTSL (0.70) CTSLCTSBCTSSCTSKTACR1
SCHEMBL10521480 0.97 CTSL (0.70) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7350864 0.94 CTSL (0.69) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7325767 0.94 CTSL (0.69) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7350862 0.93 CTSL (0.64) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7325764 0.93 CTSL (0.64) CTSLCTSBCTSSCTSKTACR1
SCHEMBL7360694 0.92 CTSS (0.63) CTSLCTSBCTSSCTSKTACR1
SCHEMBL11022927 0.91 CTSL (0.61) CTSLCTSBCTSSCTSKTACR1
SCHEMBL8335400 0.91 CTSL (0.71) CTSLCTSBCTSSCTSKTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008808-A1 Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component UNIV GUANGZHOU MEDICAL (CN) 2026-01-08 US disclosed
EP-4574834-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE WITH UNPROTECTED AMINO ACID AS AMINE COMPONENT GUANGZHOU MEDICAL UNIVERSITY (CN) 2025-06-25 EP disclosed
WO-2024139061-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE WITH UNPROTECTED AMINO ACID AS AMINE COMPONENT 广州医科大学 2024-07-04 WO disclosed
CN-116675727-A Method for synthesizing amide and/or polypeptide by taking unprotected amino acid as ammonia component 广州医科大学 2023-09-01 CN disclosed
US-5925633-A ADMINISTERING AS ANTIMETASTASIS AGENT SYNPHAR LABORATIES, INC. (CA) 1999-07-20 US disclosed
WO-1997032580-A1 3-SUBSTITUTED-4-OXA-1-AZABICYCLO[3,2,0]HEPTAN-7-ONE AS CYSTEINE PROTEASE INHIBITORS SYNPHAR LABORATORIES INC. (US) 1997-09-12 WO disclosed
US-5419966-A Solid support for synthesis of 3'-tailed oligonucleotides MICROPROBE CORPORATION (US) 1995-05-30 US disclosed
EP-0547142-A4 MICROPROBE CORP (US) 1995-01-18 EP disclosed
EP-0272671-B1 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD (CH) 1994-03-16 EP disclosed
US-5223486-A Modified oligopeptide containing a diazomethyl ketone group or methylsulfonium group UNIVERSITY RESEARCH CORPORATION (US) 1993-06-29 US disclosed
US-4188319-A ANTIBIOTICS ABBOTT LABORATORIES (US) 1980-02-12 US disclosed
US-4174312-A ACYLATION, HYDROLYSIS, SALT FORMATION, CATALYTIC HYDROGENATION ABBOTT LABORATORIES (US) 1979-11-13 US disclosed
US-4173564-A 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A ABBOTT LABORATORIES (US) 1979-11-06 US disclosed
US-4155902-A ACYLATION, HYDROGENOLYSIS ABBOTT LABORATORIES (US) 1979-05-22 US disclosed
US-4091032-A ANTIMICROBIAL AGENTS ABBOTT LABORATORIES (US) 1978-05-23 US disclosed
US-RE29369-E AMIDE PRODUCT, SALTS OF HYDROXY-SUBSTITUTED PYRIDINE COMPOUNDS KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-08-23 US disclosed
US-4043992-A Method for preparing acylated products KYOWA HAKKO KOGYO CO., LTD. (JA) 1977-08-23 US disclosed
US-3984417-A Method of producing active amino acid esters AJINOMOTO CO., INC. (JA) 1976-10-05 US disclosed
US-3963728-A ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS KYOWA HAKKO KOGYO CO., LTD. (JA) 1976-06-15 US disclosed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008808-A1 Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component ANPEP, PTMS, GCG CTSL 67/4885CTSB 1923/4885CTSS 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.