Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553050 | 0.80 | BTK (0.44) | JAK1JAK2 | |
| SCHEMBL15652027 | 0.78 | BRAF (0.33) | JAK1JAK2 | |
| SCHEMBL22103869 | 0.71 | JAK2 (0.65) | JAK1JAK2 | |
| SCHEMBL24538790 | 0.71 | JAK1 (0.40) | JAK1JAK2 | |
| SCHEMBL24539211 | 0.71 | JAK1 (0.40) | JAK1JAK2 | |
| SCHEMBL31561293 | 0.69 | JAK2 (0.43) | JAK1JAK2 | |
| SCHEMBL20039719 | 0.68 | JAK1 (0.40) | JAK1JAK2 | |
| SCHEMBL24525979 | 0.68 | JAK1 (0.40) | JAK1JAK2 | |
| SCHEMBL19192612 | 0.68 | JAK1 (0.40) | JAK1JAK2 | |
| SCHEMBL7312400 | 0.68 | BTK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541187-A | HYPOTENSIVE AGENTS | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5294612-A | Hypotensive agents and cardiovascular disorders | STERLING WINTHROP INC. (US) | 1994-03-15 | — | — | US | disclosed |