Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343747 | 0.86 | PTGS1 (0.36) | SMN1; SMN2TSHRFABP5TDP1L3MBTL1 | |
| SCHEMBL3367291 | 0.86 | THRA (0.41) | SMN1; SMN2TSHRFABP5HTTMEN1 | |
| SCHEMBL1000960 | 0.86 | THRA (0.41) | SMN1; SMN2TSHRFABP5HTTMEN1 | |
| SCHEMBL1623875 | 0.86 | PTGS1 (0.36) | SMN1; SMN2TSHRFABP5TDP1L3MBTL1 | |
| SCHEMBL6567974 | 0.82 | FABP5 (0.37) | PPARGPPARATSHRFABP5TDP1 | |
| SCHEMBL6763707 | 0.78 | L3MBTL1 (0.38) | PPARGPPARASMN1; SMN2TSHRTDP1 | |
| SCHEMBL38662011 | 0.69 | PPARA (0.47) | PPARGPPARASMN1; SMN2FABP5KMT2A | |
| SCHEMBL16057913 | 0.69 | MDM2 (0.46) | FABP5MEN1KMT2A | |
| SCHEMBL30216574 | 0.69 | MDM2 (0.46) | FABP5MEN1KMT2A | |
| SCHEMBL6567976 | 0.69 | MDM2 (0.46) | FABP5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119529-B1 | CHEMICAL CONSTRUCTS | GLAXO GROUP LTD (GB) | 2003-09-17 | — | — | EP | disclosed |
| EP-1119528-B1 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LTD (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1119529-A2 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2001-08-01 | — | — | EP | disclosed |
| EP-1119528-A2 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020357-A2 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020112-A2 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |