Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314800 | 0.89 | ITGB3 (0.50) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL6602530 | 0.89 | ITGB3 (0.60) | SIGMAR1ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7308597 | 0.88 | SIGMAR1 (0.50) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL6600105 | 0.88 | ITGB3 (0.51) | SIGMAR1ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7317117 | 0.87 | ITGB3 (0.55) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7308804 | 0.86 | ITGB3 (0.48) | SIGMAR1ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7313908 | 0.86 | ITGB3 (0.50) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7307512 | 0.86 | ITGB3 (0.47) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL7307388 | 0.86 | ITGB3 (0.47) | SIGMAR1ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL8948706 | 0.86 | ITGB3 (0.54) | SIGMAR1ITGB3ITGA2BF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |