Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858156 | 0.90 | HTR2B (0.33) | HTR2BL3MBTL1 | |
| SCHEMBL7310258 | 0.89 | MAPK1 (0.35) | HTR2BSIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL7318785 | 0.87 | MAPK1 (0.37) | HTR2BSIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL7305387 | 0.86 | HTR2B (0.36) | HTR2BSIGMAR1 | |
| SCHEMBL7311505 | 0.85 | HTR2B (0.44) | HTR2BMAOBMAPK1L3MBTL1DAO | |
| SCHEMBL7314575 | 0.85 | HTR2B (0.44) | HTR2BMAOBMAPK1L3MBTL1DAO | |
| SCHEMBL7300799 | 0.85 | HTR2B (0.44) | HTR2BMAOBMAPK1L3MBTL1DAO | |
| SCHEMBL7303510 | 0.84 | HTR2B (0.35) | HTR2BSIGMAR1 | |
| SCHEMBL7304242 | 0.83 | SIGMAR1 (0.41) | HTR2BSIGMAR1 | |
| SCHEMBL7314406 | 0.82 | ITGB3 (0.36) | HTR2BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |