Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858063 | 0.89 | ITGB3 (0.34) | SIGMAR1 | |
| SCHEMBL7318785 | 0.87 | MAPK1 (0.37) | HTR2BSIGMAR1 | |
| SCHEMBL7310258 | 0.87 | MAPK1 (0.35) | HTR2BSIGMAR1 | |
| SCHEMBL7314419 | 0.86 | SIGMAR1 (0.42) | HTR2BSIGMAR1 | |
| SCHEMBL7314744 | 0.84 | HTR2B (0.40) | HTR2BSIGMAR1 | |
| SCHEMBL7309051 | 0.83 | HTR2B (0.39) | HTR2BSIGMAR1 | |
| SCHEMBL7307995 | 0.83 | GLA (0.40) | HTR2BSIGMAR1 | |
| SCHEMBL7303856 | 0.81 | MAPK1 (0.39) | HTR2B | |
| SCHEMBL7301029 | 0.81 | HTR2B (0.43) | HTR2BSIGMAR1CYP2C19 | |
| SCHEMBL7304242 | 0.81 | SIGMAR1 (0.41) | HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |