SCHEMBL731485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9275744	0.90	TSHR (0.51)	TSHRHSD17B10POLBALOX15HTT
	SCHEMBL10111303	0.85	CREBBP (0.53)	TSHRHSD17B10HTTNCOA1NCOA3
	SCHEMBL2664838	0.84	PLA2G2A (0.54)	TSHR
	SCHEMBL1515929	0.82	TSHR (0.59)	TSHRHSD17B10POLBALOX15HTT
	SCHEMBL504156	0.82	TSHR (0.70)	TSHRPOLBALOX15HTTLMNA
	SCHEMBL9048230	0.82	CA12 (0.62)	TSHRHSD17B10POLBALOX15HTT
	SCHEMBL29633638	0.82	TSHR (0.59)	TSHRHSD17B10POLBALOX15HTT
	SCHEMBL731013	0.81	LMNA (0.50)	TSHRHSD17B10POLBNCOA1NCOA3
	SCHEMBL12603750	0.81	EGFR (0.48)	TSHRHSD17B10POLBHTTCA12
	SCHEMBL289285	0.81	CA12 (0.55)	TSHRHSD17B10NCOA1NCOA3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.