Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313931 | 0.89 | ITGB3 (0.31) | ITGB3ITGA2B | |
| SCHEMBL7305450 | 0.89 | CCR5 (0.35) | GLACCR5 | |
| SCHEMBL7304874 | 0.88 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL7310999 | 0.85 | CCR5 (0.35) | GLACCR5 | |
| SCHEMBL7303493 | 0.83 | SMN1; SMN2 (0.38) | CCR5 | |
| SCHEMBL7310439 | 0.83 | CHRM2 (0.39) | CCR5 | |
| SCHEMBL7313319 | 0.82 | MTOR (0.32) | — | |
| SCHEMBL7305780 | 0.81 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL7314434 | 0.80 | CYP1A2 (0.35) | CCR5 | |
| SCHEMBL7310309 | 0.78 | ITGB3 (0.34) | CCR5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |