Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305450 | 0.89 | CCR5 (0.35) | CCR5SMN1; SMN2ALDH1A1L3MBTL3L3MBTL1 | |
| SCHEMBL7303493 | 0.88 | SMN1; SMN2 (0.38) | CCR5SMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL7307905 | 0.88 | FKBP1A (0.32) | CCR5RECQLSMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL7308696 | 0.87 | ITGB3 (0.32) | ITGB3ITGA2BCCR5ALOX15ALDH1A1 | |
| SCHEMBL7313931 | 0.87 | ITGB3 (0.31) | ITGB3ITGA2BALOX15HSD17B10 | |
| SCHEMBL7305616 | 0.84 | SMN1; SMN2 (0.44) | RECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL7311851 | 0.83 | STS (0.38) | RECQLALDH1A1L3MBTL1 | |
| SCHEMBL7311690 | 0.82 | SMN1; SMN2 (0.41) | CCR5SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7311024 | 0.81 | SMN1; SMN2 (0.35) | CCR5SMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL7309061 | 0.80 | HSD17B10 (0.35) | RECQLSMN1; SMN2ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |