Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 11/20 | 0.36 |
| ▸ | BIRC3 | Q13489 | 9/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 9/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 2/20 | 0.34 |
| ▸ | VHL | P40337 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314971 | 1.00 | XIAP (0.36) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7314975 | 1.00 | XIAP (0.36) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7308389 | 0.86 | TACR1 (0.42) | XIAPBIRC3BIRC2ACECFD | |
| SCHEMBL7305045 | 0.84 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7305041 | 0.84 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7305036 | 0.84 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7317417 | 0.84 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7318712 | 0.78 | DPP8 (0.43) | XIAPBIRC3BIRC2ACECFD | |
| SCHEMBL7315824 | 0.76 | ALDH1A1 (0.41) | XIAPBIRC3BIRC2CFD | |
| SCHEMBL7304910 | 0.76 | F2 (0.40) | XIAPBIRC3BIRC2ACECFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |