Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715173 | 1.00 | MEN1 (0.54) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL10793551 | 0.86 | CTSL (0.57) | MEN1KMT2ATACR1ALDH1A1CTSL | |
| SCHEMBL1715348 | 0.86 | CTSL (0.57) | MEN1KMT2ATACR1ALDH1A1CTSL | |
| SCHEMBL7327394 | 0.86 | CTSL (0.57) | MEN1KMT2ATACR1ALDH1A1CTSL | |
| SCHEMBL27703700 | 0.86 | TACR1 (0.61) | RAB9ATACR1ALDH1A1 | |
| SCHEMBL883397 | 0.85 | ITGA4 (0.55) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL495975 | 0.85 | ITGA4 (0.55) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL6988240 | 0.85 | ITGA4 (0.55) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL27939979 | 0.85 | MEN1 (0.50) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL7162407 | 0.85 | MGLL (0.51) | MEN1KMT2ANPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100579957-C | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2010-01-13 | — | — | CN | disclosed |
| CN-1642906-A | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |
| EP-0272671-B1 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD (CH) | 1994-03-16 | — | — | EP | disclosed |
| US-5158936-A | Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5055451-A | Prevent tissue damage | SYNTEX INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |