Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308814 | 0.83 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7314546 | 0.82 | PDE3B (0.39) | PDE3BPDE3AMAPTTSHRMCL1 | |
| SCHEMBL7319827 | 0.79 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7320601 | 0.76 | PDE3B (0.35) | PDE3BPDE3AMAPTTSHRLMNA | |
| SCHEMBL7315274 | 0.73 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL7313632 | 0.71 | ATM (0.39) | MAPTTSHRMCL1LMNANPSR1 | |
| SCHEMBL7317428 | 0.71 | ATM (0.38) | MAPTTSHRMCL1LMNANPSR1 | |
| SCHEMBL7319259 | 0.71 | ATM (0.38) | MAPTTSHRMCL1LMNANPSR1 | |
| SCHEMBL10374578 | 0.70 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL7316653 | 0.69 | PDE3B (0.40) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |