Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310763 | 0.88 | F2 (0.33) | KMT2AL3MBTL1F2CASP6MAPT | |
| SCHEMBL7306416 | 0.88 | MAPT (0.33) | KMT2AL3MBTL1F2CASP6MAPT | |
| SCHEMBL7315270 | 0.84 | THRA (0.38) | KMT2AF2CASP6ALDH1A1THRA | |
| SCHEMBL7310371 | 0.74 | PDE3B (0.42) | THRATHRB | |
| SCHEMBL7306411 | 0.73 | THRA (0.39) | KMT2AF2MAPTALDH1A1THRA | |
| SCHEMBL7310755 | 0.73 | THRA (0.39) | KMT2AF2CASP6MAPTALDH1A1 | |
| SCHEMBL7308594 | 0.71 | NPSR1 (0.38) | KMT2ACASP6MAPTALDH1A1THRA | |
| SCHEMBL7308565 | 0.70 | SMN1; SMN2 (0.37) | KMT2AL3MBTL1CASP6MAPTALDH1A1 | |
| SCHEMBL7319790 | 0.70 | PDE3B (0.35) | KMT2AL3MBTL1CASP6MAPTALDH1A1 | |
| SCHEMBL7318251 | 0.70 | PDE3B (0.41) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |