Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310763 | 0.88 | F2 (0.33) | MAPTALDH1A1F2KMT2ATHRA | |
| SCHEMBL7315281 | 0.88 | KMT2A (0.33) | MAPTALDH1A1F2KMT2ATHRA | |
| SCHEMBL7306411 | 0.82 | THRA (0.39) | MAPTALDH1A1F2KMT2ATHRA | |
| SCHEMBL7315270 | 0.76 | THRA (0.38) | ALDH1A1F2KMT2ATHRATHRB | |
| SCHEMBL7310755 | 0.73 | THRA (0.39) | MAPTALDH1A1F2KMT2ATHRA | |
| SCHEMBL10374700 | 0.73 | SMN1; SMN2 (0.35) | MAPTALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10375053 | 0.72 | THRA (0.40) | MAPTKMT2ATHRATHRBL3MBTL1 | |
| SCHEMBL10374861 | 0.71 | L3MBTL1 (0.37) | MAPTALDH1A1KMT2ATHRATHRB | |
| SCHEMBL10376932 | 0.71 | PDE3B (0.44) | — | |
| SCHEMBL7310371 | 0.71 | PDE3B (0.42) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |