Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306411 | 0.86 | THRA (0.39) | THRATHRBF2PDE3BPDE3A | |
| SCHEMBL7310755 | 0.86 | THRA (0.39) | THRATHRBF2PDE3BPDE3A | |
| SCHEMBL7315281 | 0.84 | KMT2A (0.33) | THRATHRBF2ALDH1A1KMT2A | |
| SCHEMBL7313849 | 0.79 | L3MBTL1 (0.39) | THRATHRBPDE3BPDE3AKDM4E | |
| SCHEMBL7310371 | 0.78 | PDE3B (0.42) | THRATHRBPDE3BPDE3APDE2A | |
| SCHEMBL7315054 | 0.78 | L3MBTL1 (0.38) | PDE3BPDE3AKDM4EALDH1A1KMT2A | |
| SCHEMBL10375733 | 0.78 | PDE3B (0.39) | PDE3BPDE3AKDM4EALDH1A1KMT2A | |
| SCHEMBL10375053 | 0.77 | THRA (0.40) | THRATHRBPDE3BPDE3AKDM4E | |
| SCHEMBL7306686 | 0.77 | THRA (0.36) | THRATHRBPDE3BPDE3ACASP6 | |
| SCHEMBL7318251 | 0.76 | PDE3B (0.41) | PDE3BPDE3AKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |