Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315514 | 1.00 | CCR5 (0.61) | CCR5DRD2HTR1ADRD1DRD4 | |
| SCHEMBL25946287 | 0.84 | DRD2 (0.69) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10431424 | 0.83 | HTR1A (0.52) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10431047 | 0.83 | HTR1A (0.52) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10431422 | 0.83 | HTR1A (0.52) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10431046 | 0.83 | HTR1A (0.52) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL152587 | 0.82 | DRD2 (0.81) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL24755587 | 0.80 | DRD1 (0.70) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10441506 | 0.80 | HTR1A (0.53) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL10441505 | 0.80 | HTR1A (0.53) | DRD2HTR1ADRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639568-A1 | Piperidine compounds, their preparation and use in the treatment of neurodegenerative disorders | NOVO NORDISK A/S (DK) | 1995-02-22 | — | — | EP | claimed |
| EP-0639568-A1 | Piperidine compounds, their preparation and use in the treatment of neurodegenerative disorders | NOVO NORDISK A/S (DK) | 1995-02-22 | — | — | EP | disclosed |