Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326808 | 0.88 | TLR8 (0.48) | CSNK2A2CSNK2A1MEN1ALDH1A1MAPT | |
| SCHEMBL7331946 | 0.87 | L3MBTL1 (0.56) | L3MBTL1RARBMEN1ALDH1A1RARA | |
| SCHEMBL2388202 | 0.87 | L3MBTL1 (0.56) | L3MBTL1RARBMEN1ALDH1A1RARA | |
| SCHEMBL2952564 | 0.85 | L3MBTL1 (0.57) | L3MBTL1RARBMEN1ALDH1A1RARA | |
| SCHEMBL7323285 | 0.82 | NPC1 (0.49) | L3MBTL1RARBMEN1ALDH1A1RARA | |
| SCHEMBL8092207 | 0.79 | HDAC3 (0.48) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6538933 | 0.78 | RARB (0.76) | CSNK2A2CSNK2A1RARBMEN1ALDH1A1 | |
| SCHEMBL10401732 | 0.77 | L3MBTL1 (0.78) | L3MBTL1RARBMEN1ALDH1A1RARA | |
| SCHEMBL6538640 | 0.76 | RARB (0.75) | CSNK2A2CSNK2A1RARBMEN1ALDH1A1 | |
| SCHEMBL14147802 | 0.76 | SMPD1 (0.43) | MAPTRAB9AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |