Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314668 | 0.88 | TLR8 (0.48) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2388202 | 0.87 | L3MBTL1 (0.56) | NPC1RAB9AL3MBTL1RARBKMT2A | |
| SCHEMBL7331946 | 0.87 | L3MBTL1 (0.56) | NPC1RAB9AL3MBTL1RARBKMT2A | |
| SCHEMBL2952564 | 0.85 | L3MBTL1 (0.57) | NPC1RAB9AL3MBTL1RARBKMT2A | |
| SCHEMBL7315549 | 0.82 | CSNK2A2 (0.52) | NPC1RAB9AL3MBTL1NR1H4RARB | |
| SCHEMBL8090537 | 0.79 | HDAC3 (0.48) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10401732 | 0.77 | L3MBTL1 (0.78) | NPC1RAB9AL3MBTL1RARBKMT2A | |
| SCHEMBL7331833 | 0.75 | RARB (0.75) | NPC1RAB9ANR1H4RARBALDH1A1 | |
| SCHEMBL7342728 | 0.75 | RARB (0.75) | NPC1RAB9ANR1H4RARBALDH1A1 | |
| SCHEMBL7333177 | 0.74 | RARB (0.57) | NPC1RAB9ANR1H4RARBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |