Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315549 | 0.88 | CSNK2A2 (0.52) | CSNK2A2CSNK2A1MAPTSMN1; SMN2S1PR1 | |
| SCHEMBL7334034 | 0.88 | TLR8 (0.55) | TLR8MAPTSMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL7314668 | 0.83 | TLR8 (0.48) | TLR8MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8092207 | 0.82 | HDAC3 (0.48) | CSNK2A2CSNK2A1SMN1; SMN2GAA | |
| SCHEMBL7315645 | 0.80 | L3MBTL1 (0.53) | TLR8MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6539186 | 0.79 | CYP4A11 (0.56) | CSNK2A2CSNK2A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7320147 | 0.79 | TLR8 (0.50) | TLR8MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6539250 | 0.78 | CYP4A11 (0.57) | CSNK2A2CSNK2A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7331757 | 0.78 | RARB (0.56) | CSNK2A2CSNK2A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6539009 | 0.78 | RARB (0.56) | CSNK2A2CSNK2A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |