Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325437 | 0.86 | CAPN1 (0.52) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6939223 | 0.86 | CAPN1 (0.52) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL7787036 | 0.84 | PKM (0.54) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL7787038 | 0.84 | PKM (0.54) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL7322714 | 0.84 | AKR1C3 (0.51) | KMT2AMEN1ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL7787021 | 0.84 | CAPN1 (0.53) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL7787019 | 0.84 | CAPN1 (0.53) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL7309549 | 0.78 | AKR1C3 (0.52) | KMT2AMEN1ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL7325408 | 0.77 | AR (0.52) | KMT2AMEN1ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL7322058 | 0.77 | MEN1 (0.75) | PKMPKLRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |