Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376583 | 0.87 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1THRAKDM4EKMT2A | |
| SCHEMBL10375845 | 0.86 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1THRAKDM4EKMT2A | |
| SCHEMBL7313370 | 0.85 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRAGAAKDM4E | |
| SCHEMBL7318982 | 0.84 | TSHR (0.43) | ALDH1A1KDM4EKMT2AMAPTHTT | |
| SCHEMBL7314934 | 0.84 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1THRAGAAKDM4E | |
| Hydrochloric Acid SCHEMBL7309503 | 0.83 | TSHR (0.42) | ALDH1A1KDM4EKMT2AMAPTHTT | |
| SCHEMBL10376006 | 0.83 | ALDH1A1 (0.42) | ALDH1A1THRAGAAKDM4EKMT2A | |
| SCHEMBL7315249 | 0.81 | TNF (0.39) | ALDH1A1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL7309501 | 0.80 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1THRAKDM4EKMT2A | |
| SCHEMBL7309407 | 0.80 | TSHR (0.48) | ALDH1A1GAAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |