SCHEMBL731614

SCHEMBL731614

Cc1ccc(N=Nc2ccc(C(=O)O)cc2)c(N)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
NPC1 O15118 5/20 0.47
KMT2A Q03164 4/20 0.47
POLB P06746 3/20 0.47
MEN1 O00255 3/20 0.47
MAPT P10636 6/20 0.47
TDP1 Q9NUW8 3/20 0.47
ATM Q13315 1/20 0.47
RAB9A P51151 5/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
RPS6KA3 P51812 1/20 0.42
GLO1 Q04760 1/20 0.42
CD69 Q07108 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MAPK1 P28482 1/20 0.40
STAT3 P40763 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530980 1.00 TRPA1 (0.50) TRPA1NPC1KMT2APOLBMEN1
SCHEMBL6345168 0.80 MAPT (0.49) TRPA1NPC1KMT2AMEN1MAPT
SCHEMBL29692284 0.80 MAPT (0.49) TRPA1NPC1KMT2AMEN1MAPT
SCHEMBL2303614 0.80 TRPA1 (0.51) TRPA1NPC1KMT2APOLBMEN1
SCHEMBL29771169 0.79 TDP1 (0.47) TRPA1NPC1KMT2AMEN1MAPT
SCHEMBL8513912 0.79 MAPT (0.50) TRPA1NPC1KMT2APOLBMEN1
SCHEMBL28045110 0.79 MAPT (0.50) TRPA1NPC1KMT2APOLBMEN1
Formic Acid SCHEMBL28018206 0.79 MAPT (0.41) TRPA1NPC1KMT2AMEN1MAPT
SCHEMBL8513909 0.79 MAPT (0.50) TRPA1NPC1KMT2APOLBMEN1
SCHEMBL11523170 0.78 TRPA1 (0.56) TRPA1NPC1KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895517-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2020-12-16 EP claimed
US-9624555-B2 Sequences and methods for detecting influenza A and influenza B virus BECTON, DICKINSON AND COMPANY (US) 2017-04-18 US claimed
US-9261460-B2 Real-time nucleic acid detection processes and compositions ENZO LIFE SCIENCES, INC. (US) 2016-02-16 US claimed
EP-2267166-B1 Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification BECTON DICKINSON CO (US) 2016-01-13 EP claimed
EP-2071038-B1 Detection of herpes simplex virus types 1 and 2 by nucleic acid amplifiction BECTON DICKINSON CO (US) 2014-11-26 EP claimed
EP-2706073-A1 Two-component polyurethane composition Sika Technology AG (CH) 2014-03-12 EP claimed
US-20140004502-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS BECTON, DICKINSON AND COMPANY 2014-01-02 US claimed
EP-2267166-A1 Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification Becton Dickinson and Company (US) 2010-12-29 EP claimed
US-20100273156-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS BECTON, DICKINSON AND COMPANY (US) 2010-10-28 US claimed
EP-2152871-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS Becton, Dickinson & Company (US) 2010-02-17 EP claimed
EP-2071038-A1 Detection of herpes simplex virus types 1 and 2 by nucleic acid amplifiction Becton, Dickinson & Company (US) 2009-06-17 EP claimed
WO-2008150998-A1 SEQUENCES AND METHODS FOR DETECTING INFLUENZA A AND INFLUENZA B VIRUS BECTON, DICKINSON AND COMPANY (US) 2008-12-11 WO claimed
EP-1618214-A4 DETECTION OF HERPES SIMPLEX VIRUS TYPES 1 AND 2 BY NUCLEIC ACID AMPLIFICATION BECTON DICKINSON CO (US) 2008-02-13 EP claimed
JP-2006524512-A 2006-11-02 JP claimed
EP-1618214-A2 DETECTION OF HERPES SIMPLEX VIRUS TYPES 1 AND 2 BY NUCLEIC ACID AMPLIFICATION Becton, Dickinson and Company (US) 2006-01-25 EP claimed
WO-2004097029-A2 DETECTION OF HERPES SIMPLEX VIRUS TYPES 1 AND 2 BY NUCLEIC ACID AMPLIFICATION BECTON, DICKINSON AND COMPANY (US) 2004-11-11 WO claimed
US-20220136074-A1 ISOTHERMAL AMPLIFICATION AND AMBIENT VISUALIZATION IN A SINGLE TUBE FOR THE DETECTION OF SARS-COV-2 USING LOOP-MEDIATED AMPLIFICATION AND CRISPR TECHNOLOGY THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2022-05-05 US disclosed
US-20210285038-A1 Methods of Whole Genome Digital Amplification PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-09-16 US disclosed
EP-0826780-A1 Detection of nucleic acids using G-quartets Becton, Dickinson and Company (US) 1998-03-04 EP disclosed
US-5691145-A OLIGONUCLEOTIDE LABELLED WITH DONOR FLUOROPHORE AND ACCEPTOR DYE; DETECTING CHANGE IN FLUORESCENCE BECTON, DICKINSON AND COMPANY (US) 1997-11-25 US disclosed