SCHEMBL8513909

SCHEMBL8513909

Cc1cc(N)ccc1/N=N/c1ccc(C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
TRPA1 O75762 1/20 0.50
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
POLB P06746 3/20 0.47
ATIC P31939 1/20 0.47
SUMO2 P61956 1/20 0.47
SUMO1 P63165 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP2 Q9HC62 1/20 0.47
ATM Q13315 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 1/20 0.47
TDP1 Q9NUW8 4/20 0.47
CD69 Q07108 1/20 0.45
PHLPP2 Q6ZVD8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8513912 1.00 MAPT (0.50) MAPTNPC1RAB9ATRPA1KMT2A
SCHEMBL28045110 0.88 MAPT (0.50) MAPTNPC1RAB9ATRPA1KMT2A
SCHEMBL11523170 0.87 TRPA1 (0.56) MAPTNPC1RAB9ATRPA1KMT2A
SCHEMBL9009285 0.85 RAB9A (0.54) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL9009336 0.85 RAB9A (0.54) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL9009308 0.85 RAB9A (0.54) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL27148967 0.85 ENPP2 (0.50) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL5720474 0.84 MAPT (0.56) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL5720475 0.84 MAPT (0.56) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL27876820 0.83 MAPT (0.53) MAPTNPC1RAB9ATRPA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2457955-B1 Trisazo dyes for paper dyeing KEMIRA OYJ (FI) 2017-08-09 EP disclosed
US-9023118-B2 Azo dyes KEMIRA OYJ (FI) 2015-05-05 US disclosed
US-20130269124-A1 AZO DYES CHROMASCAPE, LLC 2013-10-17 US disclosed
WO-2012072635-A1 AZO DYES KEMIRA OYJ (FI) 2012-06-07 WO disclosed
EP-2457955-A1 Trisazo dyes for paper dyeing Kemira Oyj (FI) 2012-05-30 EP disclosed