SCHEMBL6345168

SCHEMBL6345168

Cc1ccc(N=Nc2ccccc2)c(N)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
TDP1 Q9NUW8 7/20 0.49
MAPK1 P28482 7/20 0.49
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
NPC1 O15118 5/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
CYP3A4 P08684 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
TSHR P16473 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HBB P68871 2/20 0.47
TP53 P04637 2/20 0.47
USP2 O75604 2/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.47
CHRM1 P11229 1/20 0.47
CYP2C9 P11712 1/20 0.47
DRD2 P14416 1/20 0.47
ADRA2B P18089 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692284 1.00 MAPT (0.49) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL29771169 0.98 TDP1 (0.47) MAPTTDP1MAPK1MEN1KMT2A
Formic Acid SCHEMBL28018206 0.91 MAPT (0.41) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL11116581 0.85 MAPK1 (0.58) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL28290755 0.82 ALDH1A1 (0.50) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL11400732 0.81 MAPT (0.42) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL30530980 0.80 TRPA1 (0.50) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL731614 0.80 TRPA1 (0.50) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL10714512 0.80 MAPT (0.50) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL2541892 0.77 MEN1 (0.57) MAPTTDP1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165007-A Cable material capable of indicating temperature 江苏立晟德新材料有限公司 2023-12-05 CN claimed
CN-107936667-A Thermic discoloration coating and preparation method, thermic discoloration coating, thermic discoloration composite coating, temperature indicating display device and electric appliance 杭州老板电器股份有限公司 2018-04-20 CN claimed
CN-106753342-A A kind of double-bang firecracker answers ring-type fluorescence probe and its preparation method and application 武汉大学 2017-05-31 CN claimed
CN-105779620-A Method for determining human telomere DNA lengths by using novel molecular beacons 金泽明 2016-07-20 CN claimed
CN-105694851-A Tumor-targeted diagnosis and treatment integrated fluorescent probe 武汉大学 2016-06-22 CN claimed
CN-104672300-A Double enzyme-sensitive fluorescent probe and preparation method and application thereof UNIV WUHAN 2015-06-03 CN claimed
CN-117165007-A Cable material capable of indicating temperature 江苏立晟德新材料有限公司 2023-12-05 CN disclosed
CN-115224436-A Preparation method of lithium ion battery diaphragm 惠州锂威新能源科技有限公司 2022-10-21 CN disclosed
US-10842444-B2 Systems and methods for evaluating perturbation of xenobiotic metabolism PHILIP MORRIS PRODUCTS S.A. (CH) 2020-11-24 US disclosed
CN-209644661-U A kind of portable rinses roasting device QIAN FEI 2019-11-19 CN disclosed
CN-209574347-U Portable rinses roasting device QIAN FEI 2019-11-05 CN disclosed
CN-110114520-A DNA barcode compositions and methods for in situ identification in microfluidic devices 伯克利之光生命科技公司 2019-08-09 CN disclosed
CN-106753342-B A kind of double-bang firecracker answers cyclic annular fluorescence probe and its preparation method and application 武汉大学 2019-05-24 CN disclosed
EP-1081116-A1 Ceramic article, carrier for catalyst, methods for production thereof, catalyst for producing ethylene oxide using the carrier, and method for producing ethylene oxide Nippon Shokubai Co., Ltd. (JP) 2001-03-07 EP disclosed
EP-0116951-B1 PHOTOSENSITIVE COMPOSITIONS TOSOH CORPORATION (JP) 1988-05-18 EP disclosed
EP-0086126-B1 IMIDAZOLINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL APPLICATION SYNTHELABO (FR) 1985-07-24 EP disclosed
EP-0116951-A2 Photosensitive compositions TOSOH CORPORATION (JP) 1984-08-29 EP disclosed
EP-0013643-B1 PRODUCTION OF HIGH-QUALITY AROMATIC AMINO AZO COMPOUNDS BY THE REARRANGEMENT OF 1,3-DIARYL TRIAZENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-12-08 EP disclosed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US disclosed
EP-0013643-A1 Production of high-quality aromatic amino azo compounds by the rearrangement of 1,3-diaryl triazenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-23 EP disclosed