Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304608 | 0.93 | MAPK1 (0.38) | HTR7MAPK1L3MBTL1OPRM1OPRL1 | |
| SCHEMBL7313140 | 0.87 | MAPK1 (0.39) | MAPK1L3MBTL1OPRM1OPRL1 | |
| SCHEMBL7314450 | 0.84 | HTR7 (0.41) | HTR7MAPK1L3MBTL1 | |
| SCHEMBL7306687 | 0.83 | MAPK1 (0.35) | MAPK1L3MBTL1HRH3 | |
| SCHEMBL7313654 | 0.80 | MAPK1 (0.41) | MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7314320 | 0.80 | MAPK1 (0.37) | HTR7MAPK1L3MBTL1 | |
| SCHEMBL7313926 | 0.78 | ACHE (0.51) | MAPK1L3MBTL1 | |
| SCHEMBL7304775 | 0.77 | MAPK1 (0.39) | MAPK1L3MBTL1 | |
| SCHEMBL7229039 | 0.76 | MAPK1 (0.36) | MAPK1L3MBTL1 | |
| SCHEMBL12356915 | 0.75 | HTR2B (0.40) | GRM2GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |