Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314450 | 0.88 | HTR7 (0.41) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL7305151 | 0.88 | MAPK1 (0.39) | MAPK1L3MBTL1 | |
| SCHEMBL7313140 | 0.82 | MAPK1 (0.39) | MAPK1L3MBTL1 | |
| SCHEMBL7305380 | 0.80 | MAPK1 (0.46) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL7316249 | 0.80 | HTR7 (0.35) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL7306386 | 0.80 | MAPK1 (0.47) | MAPK1L3MBTL1 | |
| SCHEMBL7316915 | 0.80 | MAPK1 (0.45) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL7304608 | 0.79 | MAPK1 (0.38) | MAPK1L3MBTL1HTR7 | |
| SCHEMBL9230345 | 0.79 | MAPK1 (0.49) | MAPK1L3MBTL1 | |
| SCHEMBL7236582 | 0.78 | CHRM2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |