Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796017 | 0.94 | DGAT1 (0.55) | ITGB3ITGA2BDGAT1ALDH1A1POLB | |
| SCHEMBL6673906 | 0.87 | ITGB3 (0.41) | ITGB3ITGA2BDGAT1ALDH1A1BRD4 | |
| SCHEMBL17551972 | 0.83 | DGAT1 (0.67) | ITGB3ITGA2BDGAT1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7314452 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BDGAT1GRIN2BMCHR1 | |
| SCHEMBL7300384 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1MAPTMCHR1 | |
| Hydrochloric Acid SCHEMBL7302230 | 0.80 | ITGB3 (0.39) | ITGB3ITGA2BMCHR1NR1H2 | |
| SCHEMBL7304447 | 0.79 | DGAT1 (0.58) | ITGB3ITGA2BDGAT1ALDH1A1POLB | |
| SCHEMBL30612421 | 0.79 | DGAT1 (0.58) | ITGB3ITGA2BDGAT1ALDH1A1POLB | |
| SCHEMBL7292707 | 0.79 | DGAT1 (0.58) | ITGB3ITGA2BDGAT1ALDH1A1POLB | |
| SCHEMBL3406500 | 0.79 | DGAT1 (0.58) | ITGB3ITGA2BDGAT1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9059234-A | — | — | None | — | — | JP | disclosed |
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |
| JP-H0959234-A | AMINO-SUBSTITUTED DICYCLIC COMPOUND AND ITS PRODUCTION | MITSUI TOATSU CHEM INC | 1997-03-04 | — | — | JP | disclosed |