Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316318 | 0.89 | SGMS2 (0.54) | SGMS2GAA | |
| SCHEMBL7317868 | 0.82 | PARP10 (0.57) | METSGMS2 | |
| SCHEMBL7318748 | 0.80 | F2 (0.51) | GAA | |
| SCHEMBL20290510 | 0.78 | LRRK2 (0.69) | SGMS2GAALRRK2 | |
| SCHEMBL7907804 | 0.78 | PARP10 (0.54) | SGMS2 | |
| SCHEMBL1554184 | 0.77 | SGMS2 (0.58) | METSGMS2GAALRRK2 | |
| SCHEMBL5968109 | 0.77 | SGMS2 (0.55) | METSGMS2 | |
| SCHEMBL7911253 | 0.77 | PARP10 (0.56) | SGMS2 | |
| SCHEMBL7349001 | 0.76 | SLC2A1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL6557646 | 0.76 | SGMS2 (0.56) | METSGMS2GAALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927035-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0927035-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5872138-A | INHIBITING LOSS OF BLOOD PLATELETS, INHIBITING FORMATION OF BLOOD PLATELET AGGREGATES, INHIBITING FORMATION OF FIBRIN, INHIBITING THROMBUS FORMATION, AND INHIBITING EMBOLUS FORMATION IN A MAMMAL | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1998010763-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1998-03-19 | — | — | WO | disclosed |