Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319871 | 1.00 | CTSK (0.46) | CTSKMMEECE1ACE2 | |
| SCHEMBL7323956 | 1.00 | CTSK (0.46) | CTSKMMEECE1ACE2 | |
| SCHEMBL7314091 | 1.00 | CTSK (0.46) | CTSKMMEECE1ACE2 | |
| SCHEMBL7383267 | 1.00 | CTSK (0.46) | CTSKMMEECE1ACE2 | |
| SCHEMBL7316826 | 0.90 | ANPEP (0.49) | CTSK | |
| SCHEMBL9492277 | 0.90 | ANPEP (0.49) | CTSK | |
| SCHEMBL7324927 | 0.90 | ANPEP (0.49) | CTSK | |
| SCHEMBL7309270 | 0.88 | CTSL (0.46) | MMEECE1 | |
| SCHEMBL7309259 | 0.88 | CTSL (0.46) | MMEECE1 | |
| SCHEMBL7329474 | 0.88 | CTSL (0.46) | MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212163-A | Phosphonate dipeptide or tripeptide derivatives as collagenase inhibitors for treatment of connective tissue disorders | BEECHAM GROUP P.L.C. (GB) | 1993-05-18 | — | — | US | disclosed |
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| EP-0401963-A1 | Phosphonopeptides with collagenase inhibiting activity | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |