Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | CPA2 | P48052 | 2/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309259 | 1.00 | CTSL (0.46) | CTSLCPA1CPA2CPA4MME | |
| SCHEMBL7309270 | 1.00 | CTSL (0.46) | CTSLCPA1CPA2CPA4MME | |
| SCHEMBL7315045 | 0.92 | CPA1 (0.45) | CTSLCPA1CPA2CPA4MME | |
| SCHEMBL7315037 | 0.92 | CPA1 (0.45) | CTSLCPA1CPA2CPA4MME | |
| SCHEMBL7305566 | 0.92 | CPA1 (0.45) | CTSLCPA1CPA2CPA4MME | |
| SCHEMBL7317922 | 0.91 | MMP1 (0.47) | CTSLMMP3MMP1MEN1KMT2A | |
| SCHEMBL7316369 | 0.88 | CTSK (0.46) | MMEECE1 | |
| SCHEMBL7323956 | 0.88 | CTSK (0.46) | MMEECE1 | |
| SCHEMBL7383267 | 0.88 | CTSK (0.46) | MMEECE1 | |
| SCHEMBL7314091 | 0.88 | CTSK (0.46) | MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |