Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 4/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318689 | 0.85 | LMNA (0.51) | CTRB1LMNATSHRHPGDSMEN1 | |
| SCHEMBL7311069 | 0.85 | LMNA (0.51) | CTRB1LMNATSHRHPGDSMEN1 | |
| SCHEMBL12310933 | 0.85 | MEN1 (0.64) | CTRB1LMNAMEN1KMT2APRCP | |
| SCHEMBL28260728 | 0.85 | MEN1 (0.64) | CTRB1LMNAMEN1KMT2APRCP | |
| SCHEMBL12640063 | 0.85 | MEN1 (0.64) | CTRB1LMNAMEN1KMT2APRCP | |
| SCHEMBL12757448 | 0.84 | LMNA (0.53) | LMNATSHRHPGDSMEN1KMT2A | |
| SCHEMBL7371275 | 0.82 | SLC6A9 (0.53) | CTRB1TSHRKMT2A | |
| SCHEMBL3175279 | 0.81 | CTRB1 (0.59) | CTRB1LMNATAAR1MEN1KMT2A | |
| SCHEMBL891425 | 0.81 | CTRB1 (0.59) | CTRB1LMNATAAR1XIAPMEN1 | |
| SCHEMBL31656407 | 0.81 | CTRB1 (0.59) | CTRB1LMNATAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |