Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311075 | 1.00 | LMNA (0.47) | LMNAALOX5GAAMMETSHR | |
| SCHEMBL7315861 | 0.86 | ACP3 (0.47) | LMNAALOX5ALDH1A1KMT2AHPGD | |
| SCHEMBL334678 | 0.84 | ALOX5 (0.42) | LMNAALOX5MMEALDH1A1TRPM8 | |
| SCHEMBL7314848 | 0.83 | MEN1 (0.52) | LMNAALOX5TSHRALDH1A1TRPM8 | |
| SCHEMBL27488761 | 0.83 | MEN1 (0.52) | LMNAALOX5TSHRALDH1A1TRPM8 | |
| SCHEMBL7316181 | 0.83 | MEN1 (0.52) | LMNAALOX5TSHRALDH1A1TRPM8 | |
| Hydrochloric Acid SCHEMBL8614874 | 0.82 | MEN1 (0.51) | LMNAALOX5TSHRALDH1A1TRPM8 | |
| SCHEMBL7316408 | 0.81 | LMNA (0.50) | LMNAALOX5GAATSHRALDH1A1 | |
| SCHEMBL7317181 | 0.76 | APAF1 (0.46) | LMNAALOX5MMEEPHX1BCAT2 | |
| SCHEMBL7318383 | 0.76 | APAF1 (0.46) | LMNAALOX5MMEEPHX1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |