Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308087 | 0.86 | LMNA (0.58) | LMNABRD4BRD2BRD3HPGD | |
| SCHEMBL7316606 | 0.81 | LMNA (0.52) | LMNABRD4BRD2BRD3HPGD | |
| Imidazole SCHEMBL7316456 | 0.81 | LMNA (0.51) | LMNABRD4BRD2BRD3HPGD | |
| SCHEMBL7306642 | 0.76 | GABRA1 (0.48) | LMNAPDE4DGABRA1GABRA5GABRA3 | |
| SCHEMBL7313820 | 0.74 | GABRA1 (0.48) | LMNAPDE4DGABRA1GABRA5GABRA3 | |
| SCHEMBL7310152 | 0.73 | OPRK1 (0.60) | LMNABRD4HPGDPDE4DGABRA1 | |
| SCHEMBL7318178 | 0.73 | LMNA (0.62) | LMNABRD4BRD2BRD3HPGD | |
| SCHEMBL7324713 | 0.72 | GABRA1 (0.67) | LMNABRD4BRD2BRD3HPGD | |
| SCHEMBL29407473 | 0.72 | GABRA1 (0.67) | LMNABRD4BRD2BRD3HPGD | |
| SCHEMBL7308179 | 0.72 | OPRK1 (0.56) | LMNABRD4HPGDPDE4DGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | disclosed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | disclosed |
| EP-0109921-A1 | Benzodiazepine receptors and their preparation | A/S FERROSAN (DK) | 1984-05-30 | — | — | EP | disclosed |