Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321697 | 0.88 | PARP1 (0.54) | POLBPARP1LMNADAOHTT | |
| SCHEMBL7318431 | 0.76 | PARP1 (0.56) | PARP1ALDH1A1CYP2C9DAOKDM4E | |
| SCHEMBL7316537 | 0.74 | PARP1 (0.46) | POLBPARP1ALDH1A1HPGDCYP2C9 | |
| SCHEMBL11816803 | 0.73 | ALDH1A1 (0.53) | POLBPARP1ALDH1A1HPGDCYP2C9 | |
| SCHEMBL23886056 | 0.70 | CAPN1 (0.55) | POLBPARP1ALDH1A1HPGDCYP2C9 | |
| SCHEMBL168776 | 0.70 | PARP1 (1.00) | PARP1KMT2AMEN1 | |
| SCHEMBL29900512 | 0.70 | PARP1 (1.00) | PARP1KMT2AMEN1 | |
| SCHEMBL312985 | 0.70 | POLB (0.40) | POLBPARP1ALDH1A1HPGD | |
| SCHEMBL7323966 | 0.70 | PARP1 (0.56) | POLBPARP1ALDH1A1HPGDLMNA | |
| SCHEMBL7323950 | 0.70 | PARP1 (0.56) | POLBPARP1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071913-A | 2-(1H-TETRAZOL-5-YL)-4'-(AS-TRIAZIN-YLMETHYL)BIPHENYLS; CARDIOVASCULAR DISEASES, ESPECIALLY HYPERTENSION AND CONGESTIVE HEART FAILURE | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2000-06-06 | — | — | US | disclosed |