Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019681 | 0.94 | PLK1 (0.60) | RARBPLK1THRBALDH1A1POLB | |
| SCHEMBL12656104 | 0.89 | RARB (0.72) | RARBPLK1THRBALDH1A1MAPT | |
| SCHEMBL11554077 | 0.87 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL8103655 | 0.87 | RARB (0.59) | RARBPLK1THRBALDH1A1POLB | |
| SCHEMBL9159711 | 0.86 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL8132083 | 0.86 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL6024252 | 0.86 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL9437181 | 0.86 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL10453829 | 0.86 | RARB (0.73) | RARBTHRBALDH1A1MAPTKMT2A | |
| SCHEMBL7123177 | 0.84 | ALDH1A1 (0.57) | RARBPLK1ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592219-B | Compound, optical film and method for making optical film | 住友化学株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-104592219-A | Compound, optical film and method for making optical film | SUMITOMO CHEMICAL CO | 2015-05-06 | — | — | CN | disclosed |
| CN-101838264-B | Compound, optical film, and method for producing optical film | SUMITOMO CHEMICAL CO | 2014-12-03 | — | — | CN | disclosed |
| US-20120273725-A1 | Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | KENT STATE UNIVERSITY (US) | 2012-11-01 | — | — | US | disclosed |
| CN-101838264-A | Compound, optical film, and method for producing optical film | SUMITOMO CHEMICAL CO | 2010-09-22 | — | — | CN | disclosed |
| US-7534547-B2 | Optically active compound and photosensitive resin composition | OSAKA GAS COMPANY LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |
| US-7534547-B2 | Optically active compound and photosensitive resin composition | OSAKA GAS COMPANY LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |
| EP-0805813-B1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID CO (US) | 2002-05-15 | — | — | EP | disclosed |
| US-5780471-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1996022292-A1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5521173-A | TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4073742-A | Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120273725-A1 | Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | DHCR7, CYP7A1, CCR7 | RARB 1850/4885PLK1 3804/4885THRB 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.