Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7317675 | 0.99 | PKM (0.44) | PKMADORA2AALOX15 | |
| SCHEMBL7319679 | 0.86 | ALOX15 (0.35) | ADORA2AALOX15ALDH1A1LMNANPSR1 | |
| SCHEMBL7678306 | 0.86 | ADORA2A (0.52) | ADORA2AALOX15 | |
| Hydrochloric Acid SCHEMBL7319888 | 0.85 | ALOX15 (0.35) | ADORA2AALOX15ALDH1A1LMNANPSR1 | |
| SCHEMBL7680843 | 0.84 | HRH3 (0.36) | ADORA2AALOX15ALDH1A1LMNANPSR1 | |
| SCHEMBL7680781 | 0.84 | HRH3 (0.39) | ADORA2AALOX15 | |
| SCHEMBL7316596 | 0.82 | BCHE (0.47) | PKM | |
| Hydrochloric Acid SCHEMBL7317679 | 0.82 | PKM (0.46) | PKM | |
| SCHEMBL7677866 | 0.80 | NPC1 (0.54) | PKMADORA2AALOX15ALDH1A1 | |
| SCHEMBL7678155 | 0.79 | PSEN1 (0.41) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |