Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307106 | 0.85 | L3MBTL1 (0.42) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10758202 | 0.84 | MAPT (0.41) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10754794 | 0.84 | MAPT (0.41) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL7315213 | 0.84 | L3MBTL1 (0.43) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10374669 | 0.84 | L3MBTL1 (0.45) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10377228 | 0.84 | L3MBTL1 (0.45) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10374908 | 0.83 | L3MBTL1 (0.42) | BCHEACHEKDM4EL3MBTL1MAPT | |
| SCHEMBL10756382 | 0.80 | MAPT (0.40) | KDM4EL3MBTL1MAPTALDH1A1NPC1 | |
| SCHEMBL7304281 | 0.80 | NPC1 (0.46) | KDM4EL3MBTL1MAPTALDH1A1NPC1 | |
| SCHEMBL10374681 | 0.79 | THRA (0.43) | KDM4EL3MBTL1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |