Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307106 | 0.85 | L3MBTL1 (0.42) | L3MBTL1BCHEACHEKDM4ECYP2D6 | |
| SCHEMBL7316610 | 0.84 | BCHE (0.40) | L3MBTL1BCHEACHEKDM4ECYP2D6 | |
| SCHEMBL7317245 | 0.75 | PDE3B (0.44) | L3MBTL1KDM4ECYP2D6CYP2C19MEN1 | |
| SCHEMBL7307955 | 0.74 | L3MBTL1 (0.43) | L3MBTL1BCHEACHEKDM4ECYP2D6 | |
| SCHEMBL10375733 | 0.73 | PDE3B (0.39) | L3MBTL1KDM4ECYP2D6CYP2C19MAPT | |
| SCHEMBL10376737 | 0.72 | ALDH1A1 (0.39) | L3MBTL1BCHEACHEKDM4ELMNA | |
| SCHEMBL7313849 | 0.71 | L3MBTL1 (0.39) | L3MBTL1KDM4ECYP2D6CYP2C19KMT2A | |
| SCHEMBL10377102 | 0.71 | BACE1 (0.38) | L3MBTL1BCHEACHEKDM4ECYP2D6 | |
| SCHEMBL10374904 | 0.71 | BACE1 (0.38) | BCHEACHEKDM4ERAB9AMEN1 | |
| SCHEMBL7320520 | 0.70 | PDE3B (0.47) | KDM4ECYP2C19MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |