Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.57 |
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306604 | 0.79 | MAPT (0.46) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL844316 | 0.77 | CTSK (0.73) | CTSKCTSSCYP2C19CTSLCTSB | |
| SCHEMBL2481878 | 0.77 | CTSK (0.73) | CTSKCTSSCYP2C19CTSLCTSB | |
| SCHEMBL844317 | 0.77 | CTSK (0.73) | CTSKCTSSCYP2C19CTSLCTSB | |
| SCHEMBL7317017 | 0.76 | CTSK (0.47) | CTSKCTSSLMNAALDH1A1 | |
| SCHEMBL8083650 | 0.76 | PPARG (0.45) | CTSKCTSSPKMCYP2C19CTSL | |
| SCHEMBL7306181 | 0.76 | CYP2C19 (0.50) | PKMCYP2C19CTSCLMNAALDH1A1 | |
| SCHEMBL8083658 | 0.75 | CTSK (0.46) | CTSKCTSSCTSLLMNACTSB | |
| SCHEMBL20830986 | 0.75 | CTSK (0.73) | CTSKCTSSCTSCCTSLCTSB | |
| SCHEMBL9109956 | 0.73 | CTSK (0.68) | CTSKCTSSCYP2C19CTSCCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |