Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301520 | 0.84 | CTSK (0.44) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL7304463 | 0.83 | CYP1A2 (0.43) | NPSR1ALDH1A1CTSKCTSSCTSL | |
| SCHEMBL8083658 | 0.83 | CTSK (0.46) | MAPTNPSR1RECQLALDH1A1CTSK | |
| SCHEMBL8083650 | 0.82 | PPARG (0.45) | MAPTALDH1A1CTSKCTSSCTSL | |
| SCHEMBL7317017 | 0.82 | CTSK (0.47) | MAPTALDH1A1CTSKCTSSREN | |
| SCHEMBL10630212 | 0.81 | CTSK (0.57) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL7304711 | 0.81 | CTSK (0.44) | MAPTNPSR1RECQLALDH1A1CTSK | |
| SCHEMBL7307182 | 0.81 | CTSK (0.44) | MAPTNPSR1RECQLALDH1A1CTSK | |
| SCHEMBL7316620 | 0.79 | CTSK (0.57) | ALDH1A1CTSKCTSSCTSLCTSB | |
| SCHEMBL8086793 | 0.79 | KMT2A (0.52) | NPSR1ALDH1A1CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |