Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306604 | 0.82 | MAPT (0.46) | CTSKCTSSMAPTALDH1A1CTSL | |
| SCHEMBL7317017 | 0.81 | CTSK (0.47) | CTSKCTSSMAPTALDH1A1KDM4E | |
| SCHEMBL8083658 | 0.77 | CTSK (0.46) | CTSKCTSSMAPTALDH1A1GAA | |
| SCHEMBL7316620 | 0.76 | CTSK (0.57) | CTSKCTSSALDH1A1PKMCYP2C19 | |
| SCHEMBL8075350 | 0.76 | KMT2A (0.52) | CTSKCTSSALDH1A1KDM4EHPGD | |
| SCHEMBL8086793 | 0.76 | KMT2A (0.52) | CTSKCTSSALDH1A1KDM4EHPGD | |
| SCHEMBL7307221 | 0.76 | LMNA (0.41) | MAPTALDH1A1GAAPKMHPGD | |
| SCHEMBL7307182 | 0.75 | CTSK (0.44) | CTSKCTSSMAPTALDH1A1 | |
| SCHEMBL7304711 | 0.75 | CTSK (0.44) | CTSKCTSSMAPTALDH1A1 | |
| SCHEMBL6862901 | 0.72 | ALDH1A1 (0.51) | CTSKCTSSALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |