Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304422 | 0.87 | CTSL (0.50) | EBPSIGMAR1CTSKCTSLCTSS | |
| SCHEMBL7312048 | 0.85 | FNTA (0.39) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7313580 | 0.85 | FNTA (0.39) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7316235 | 0.85 | FNTA (0.39) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7309770 | 0.84 | EBP (0.44) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7314206 | 0.83 | EBP (0.43) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7307758 | 0.83 | EBP (0.43) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7305253 | 0.83 | EBP (0.41) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7304195 | 0.83 | EBP (0.41) | EBPSIGMAR1L3MBTL1CTSKCTSL | |
| SCHEMBL7315356 | 0.81 | CTSS (0.46) | EBPSIGMAR1L3MBTL1CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |