Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543312 | 0.85 | KMT2A (0.47) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| SCHEMBL4609738 | 0.84 | ESR1 (0.57) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| SCHEMBL28522393 | 0.84 | CYP1A2 (0.48) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| SCHEMBL16756212 | 0.79 | L3MBTL1 (0.70) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| SCHEMBL3133638 | 0.77 | ELANE (0.58) | L3MBTL1KMT2APOLBALDH1A1TSHR | |
| SCHEMBL16756229 | 0.76 | KMT2A (0.64) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| SCHEMBL16756223 | 0.76 | ESR1 (0.63) | L3MBTL1MEN1KMT2ARAB9APOLB | |
| Hydrochloric Acid SCHEMBL21410019 | 0.76 | ELANE (0.57) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL28125954 | 0.76 | ELANE (0.57) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL338196 | 0.75 | PTGS2 (0.68) | RAB9AESR1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |