Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323803 | 0.93 | MAPT (0.60) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL542658 | 0.89 | MAPT (0.66) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8949705 | 0.84 | MAPT (0.60) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8092371 | 0.83 | MAPT (0.49) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7323088 | 0.82 | NR1H4 (0.50) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7321165 | 0.81 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7322270 | 0.81 | MAPT (0.64) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7338304 | 0.81 | MAPT (0.64) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL9288915 | 0.80 | ADRB2 (0.55) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL10580996 | 0.80 | MAPT (0.51) | MAPTNPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240713-C | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1296494-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |