Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542658 | 0.95 | MAPT (0.66) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7323803 | 0.91 | MAPT (0.60) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8567735 | 0.89 | RAB9A (0.50) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5204910 | 0.85 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7317153 | 0.84 | MAPT (0.55) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL26041373 | 0.82 | CA1 (0.49) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8916998 | 0.82 | MAPT (0.71) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5059126 | 0.82 | MAPT (0.70) | MAPTRAB9ANPC1SMN1; SMN2CA1 | |
| SCHEMBL5059128 | 0.82 | MAPT (0.70) | MAPTRAB9ANPC1SMN1; SMN2CA1 | |
| SCHEMBL8092371 | 0.81 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |