Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323803 | 0.89 | MAPT (0.60) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL542658 | 0.85 | MAPT (0.66) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL7317153 | 0.83 | MAPT (0.55) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL8949705 | 0.81 | MAPT (0.60) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL7323088 | 0.79 | NR1H4 (0.50) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL9288915 | 0.77 | ADRB2 (0.55) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL10580680 | 0.76 | MAPT (0.51) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL10580996 | 0.76 | MAPT (0.51) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL10580343 | 0.76 | MAPT (0.51) | MAPTADRB2ADRB1ADRB3RAB9A | |
| SCHEMBL12379814 | 0.76 | MAPT (0.51) | MAPTADRB2ADRB1ADRB3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |