Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317343 | 1.00 | CA2 (0.45) | CA2CA1LTA4HMMECA12 | |
| SCHEMBL7317378 | 1.00 | CA2 (0.45) | CA2CA1LTA4HMMECA12 | |
| SCHEMBL7307690 | 0.88 | MME (0.49) | LTA4HMME | |
| SCHEMBL7307744 | 0.88 | MME (0.49) | LTA4HMME | |
| SCHEMBL7322360 | 0.88 | MME (0.49) | LTA4HMME | |
| SCHEMBL7307711 | 0.88 | MME (0.49) | LTA4HMME | |
| SCHEMBL7347192 | 0.86 | KMO (0.43) | LTA4HMME | |
| SCHEMBL7347170 | 0.86 | KMO (0.43) | LTA4HMME | |
| SCHEMBL7347160 | 0.86 | KMO (0.43) | LTA4HMME | |
| SCHEMBL7314261 | 0.86 | GPR34 (0.42) | LTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |